By David C. Lloyd (auth.), Priv.-Doz. Dr. Dr. Wolfgang G. Eisert, Dr. Mortimer L. Mendelsohn (eds.)
In October 1982, a small overseas symposium was once held on the Gesellschaft fUr Strahlen- und Umweltforschung mbH (GSF) in Munich as a satellite tv for pc assembly of the IX foreign convention on Analytical Cytology. The symposium focussed on cytometric techniques to organic dosimetry, and used to be, to the simplest of our wisdom, the 1st assembly in this topic ever held. there has been powerful encouragement from the seventy five attendees and from others to post a lawsuits of the symposium. accordingly this ebook, containing 30 of the 36 displays, has been assembled. Dosimetry, the exact and systematic selection of doses, frequently refers to grams of substance administered or rads of ionization or a few such degree of publicity of a sufferer, a sufferer or an experimental process. The time period can even be used to explain the volume of an final, energetic agent as brought to the right goal fabric inside of a organic approach. therefore, for mutagens, you'll be able to communicate of DNA dosimetry, that means the variety of adducts produced within the DNA of goal cells similar to bone-mar row stem cells or spermatogonia.
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Extra info for Biological Dosimetry: Cytometric Approaches to Mammalian Systems
Springer, Berlin 44. Salamone M, Heddle J, Stuart E, Katz M (1980) Towards an improved micronucleus test. Studies on 3 model agents, mitomycin C, cyclophosphamide and dimethylbenzanthracene. Mutat Res 74:347-356 45. Salamone MF, Heddle JA, Katz M (1981) Mutagenic activity of 41 compounds in the in vivo micronucleus assay. In: DeSerres JF, Ashby J (eds) Evaluation of short-term tests for carcinogens. Elsevier/North-Holland, New York Amsterdam Oxford, pp 686-697 46. Schmid W, Arakaki DT, Breslau NA, Culbertson JC (1971) Chemicalmutagenesis: the Chinese hamster bone marrow as an in vivo test system.
Mutation Res 91:251-254 16. Lloyd DC, Purrott RJ (1981) Chromosome aberration analysis in radiological protection dosimetry. Radiation Protection Dosimetry 1: 19-28 17. Luchnik NY, Sevankaev AV (1976) Radiation-induced chromosomal aberrations in human lymphocytes. I. Dependence on the dose of '}'-rays and an anQmaly at low doses. Mutation Res 36:363-378 18. Otake M (1979) The nonlinear relationship of radiation dose to chromosome aberrations among atomic bomb survivors, Hiroshima and Nagasaki. Report on Radiation Effects Research Foundation, Research Project 2-66, RERF TR 19-78 pp 1-19 19.
Cytogenetic results on basic aspects of the methodology, obtained with alkylating agents. Humangenetik 11: 103-118 47. Schumann J, Tilkorn H, Giihde W, Ehring F, Straub C (1981) Zytogenetik maligner Melanome. Hautarzt Suppl V:62-66 48. Sugiyama T (1973) Chromosomal aberrations and carcinogenesis by various benz(a) anthracene derivatives. Gann 64:637 -639 49.
Biological Dosimetry: Cytometric Approaches to Mammalian Systems by David C. Lloyd (auth.), Priv.-Doz. Dr. Dr. Wolfgang G. Eisert, Dr. Mortimer L. Mendelsohn (eds.)