Download PDF by J. F. Lawless, K. Singhal (auth.), Ian B. MacNeill, Gary J.: Biostatistics: Advances in Statistical Sciences Festschrift

By J. F. Lawless, K. Singhal (auth.), Ian B. MacNeill, Gary J. Umphrey, Allan Donner, V. Krishna Jandhyala (eds.)

ISBN-10: 9400947941

ISBN-13: 9789400947948

ISBN-10: 9401086265

ISBN-13: 9789401086264

On might 27-31, 1985, a chain of symposia used to be held on the collage of Western Ontario, London, Canada, to have a good time the seventieth birthday of professional­ fessor V. M. Joshi. those symposia have been selected to mirror Professor Joshi's examine pursuits in addition to components of craftsmanship in statistical technology between school within the Departments ofStatistical and Actuarial Sciences, Economics, Epidemiology and Biostatistics, and Philosophy. From those symposia, the six volumes which contain the "Joshi Festschrift" have arisen. The 117 articles during this paintings mirror the large pursuits and prime quality of study of these who attended our convention. we want to thank all the participants for his or her extraordinary cooperation in assisting us to accomplish this undertaking. Our inner most gratitude needs to visit the 3 those that have spent a lot in their time some time past yr typing those volumes: Jackie Bell, Lise consistent, and Sandy Tarnowski. This paintings has been revealed from "camera prepared" replica produced by way of our Vax 785 laptop and QMS Lasergraphix printers, utilizing the textual content processing software program TEX. on the initiation of this undertaking, we have been neophytes inthe use ofthis approach. thanks, Jackie, Lise, and Sandy, for having the patience and commitment had to entire this undertaking.

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M. Durie, J. Grenier, and J. Sany (1985), "Prognostic factors and staging in multiple myeloma: are-appraisal". Journal of Clinical Oncology (in press). , J. H. Friedman, R. A. Olshen, and C. J. Stone (1984), Classification and Regression Trees. Belmont, CA: Wadsworth. Byar, D. P. (1982), "Analysis of survival data: Cox and Weibull models with covariates". In Statistics in Medical Research, ed. V. Mike and K. E. Stanley, pp. 365-401. New York: Wiley and Sons. Cox, D. R. (1972), "Regression models and life tables" (with discussion).

HOGG AND S. McKINNEY Table 2. Multiple Myeloma Variables Used by the Stepwise Cox Proportional Hazards Regression Algorithm (BMDP2L) Zl Z2 I I Z3 I Z4 I Zs I Z6 I Z7 I Zs I Zg = I ZIO = I Zll = I Z12 I Z13 I Z14 = I ZIS I Z16 = I lex) lex) (Haemoglobin = mildly depressed) (Haemoglobin = normal) (Calcium = mildly elevated) (Calcium = severely elevated) (Creatinine = mildly elevated) (Creatinine = severely elevated) (Alk. Phos. = mildly elevated) (Alk. Phos. = severely elevated) (White Blood Cell % Plasma> 0%) (Bone Marrow % Plasma = trace) (Bone Marrow % Plasma = elevated) (4 or more lytic lesions) (Age 45-60 years) (Age over 60 years) (Symptoms lasted 30 or more months) (M-protein risk factor = high risk) 1 if the logical statement X.

1984) via the idea of resampling schemes. This formulation and the use of likelihood based measures of model significance allows us to use the AIC instead of the more expensive cross-validation or bootstrap calculations for the selection of "honest" trees. The examples discussed in this paper illustrate the flexibility of the framework and its usefulness in the clinical context. They show that RP produces results of clear interpretability and are therefore attractive to physicians. From a statistical point of view, and if we adopt the AIC as a criterion for model comparison, the examples show that RP based models compare well or favourably with those obtained by stepwise regression.

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Biostatistics: Advances in Statistical Sciences Festschrift in Honor of Professor V.M. Joshi’s 70th Birthday Volume V by J. F. Lawless, K. Singhal (auth.), Ian B. MacNeill, Gary J. Umphrey, Allan Donner, V. Krishna Jandhyala (eds.)


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